Samarium in PDB 1cx8: Crystal Structure of the Ectodomain of Human Transferrin Receptor

The structure of Crystal Structure of the Ectodomain of Human Transferrin Receptor, PDB code: 1cx8 was solved by C.M.Lawrence, S.Ray, M.Babyonyshev, R.Galluser, D.Borhani, S.C.Harrison, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 3.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	105.400, 216.900, 361.900, 90.00, 90.00, 90.00
R / Rfree (%)	24.3 / 28.4

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 24;

Binding sites:

The binding sites of Samarium atom in the Crystal Structure of the Ectodomain of Human Transferrin Receptor (pdb code 1cx8). This binding sites where shown within 5.0 Angstroms radius around Samarium atom.
In total 24 binding sites of Samarium where determined in the Crystal Structure of the Ectodomain of Human Transferrin Receptor, PDB code: 1cx8:
Jump to Samarium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Samarium binding site 1 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 1 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ A:Sm764 b:2.0 occ:1.00 OD1 A:ASP757 2.2 3.2 1.0 CG A:ASP757 2.4 21.2 1.0 OD2 A:ASP648 2.5 45.3 1.0 OD1 A:ASP648 2.6 31.9 1.0 OD2 A:ASP757 2.7 20.8 1.0 CG A:ASP648 2.8 52.1 1.0 CB A:ASP757 3.2 48.6 1.0 O A:ASP757 3.9 85.4 1.0 NE2 A:GLN743 4.0 55.9 1.0 CB A:ASP648 4.2 60.2 1.0 CA A:ASP757 4.4 88.6 1.0 C A:ASP757 4.6 92.0 1.0 CB A:SER644 4.9 71.0 1.0 N A:ASP757 5.0 98.7 1.0

Samarium binding site 2 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 2 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ A:Sm765 b:2.0 occ:1.00 OG1 A:THR310 1.9 2.0 1.0 OE1 A:GLU465 2.0 2.7 1.0 O A:THR310 2.0 2.8 1.0 OE2 A:GLU468 2.3 2.0 1.0 C A:THR310 2.6 50.5 1.0 CB A:THR310 2.7 17.5 1.0 OE1 A:GLU468 2.7 2.0 1.0 CD A:GLU465 2.7 29.8 1.0 CD A:GLU468 2.8 24.7 1.0 OE2 A:GLU465 2.9 4.3 1.0 O A:ASP307 2.9 70.2 1.0 CG2 A:THR310 3.0 52.2 1.0 CA A:THR310 3.0 50.4 1.0 N A:THR310 3.4 68.9 1.0 N A:PRO311 3.6 65.2 1.0 CB A:ASP307 3.8 87.6 1.0 C A:ASP307 3.9 61.9 1.0 O A:PHE313 4.0 85.2 1.0 CG A:GLU465 4.1 45.4 1.0 N A:ASP307 4.2 64.2 1.0 CA A:ASP307 4.2 70.7 1.0 CA A:PRO311 4.3 65.9 1.0 CG A:GLU468 4.3 35.9 1.0 OD1 A:ASP307 4.5 87.2 1.0 CG A:ASP307 4.5 96.0 1.0 C A:TYR309 4.7 65.7 1.0 CD A:PRO311 4.7 51.2 1.0 C A:GLY306 4.8 66.8 1.0 N A:TYR309 4.9 52.0 1.0 N A:GLY312 4.9 75.9 1.0

Samarium binding site 3 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 3 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ A:Sm766 b:34.2 occ:1.00 OE2 A:GLU578 2.6 51.9 1.0 OE2 A:GLU575 3.0 92.8 1.0 OE1 A:GLU578 3.1 44.7 1.0 CD A:GLU578 3.2 64.1 1.0 OE1 A:GLU575 3.3 98.7 1.0 CD A:GLU575 3.6 98.7 1.0 CG A:GLU578 4.6 85.2 1.0

Samarium binding site 4 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 4 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ B:Sm764 b:2.0 occ:1.00 CG B:ASP757 2.3 25.5 1.0 OD1 B:ASP757 2.3 24.0 1.0 OD2 B:ASP757 2.6 24.3 1.0 OD2 B:ASP648 2.6 42.2 1.0 OD1 B:ASP648 2.6 33.3 1.0 CB B:ASP757 2.9 53.0 1.0 CG B:ASP648 2.9 51.6 1.0 O B:ASP757 3.6 96.6 1.0 CA B:ASP757 4.2 88.0 1.0 NE2 B:GLN743 4.3 72.6 1.0 C B:ASP757 4.3 96.0 1.0 CB B:ASP648 4.4 47.3 1.0 N B:ASP757 4.8 96.9 1.0

Samarium binding site 5 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 5 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ B:Sm765 b:2.0 occ:1.00 OG1 B:THR310 1.9 2.0 1.0 OE1 B:GLU465 1.9 2.0 1.0 O B:THR310 2.0 2.0 1.0 OE2 B:GLU468 2.2 6.7 1.0 C B:THR310 2.6 52.0 1.0 CD B:GLU465 2.6 24.3 1.0 OE1 B:GLU468 2.6 2.0 1.0 CB B:THR310 2.7 38.5 1.0 CD B:GLU468 2.7 38.8 1.0 OE2 B:GLU465 2.7 2.0 1.0 O B:ASP307 3.0 68.7 1.0 CA B:THR310 3.0 50.9 1.0 CG2 B:THR310 3.0 52.8 1.0 N B:THR310 3.4 66.3 1.0 N B:PRO311 3.6 68.7 1.0 CB B:ASP307 3.9 80.2 1.0 C B:ASP307 4.0 49.6 1.0 O B:PHE313 4.0 68.5 1.0 CG B:GLU465 4.0 41.1 1.0 CG B:GLU468 4.2 44.7 1.0 N B:ASP307 4.2 62.5 1.0 CA B:PRO311 4.2 64.7 1.0 CA B:ASP307 4.3 58.9 1.0 OD1 B:ASP307 4.5 98.7 1.0 CG B:ASP307 4.6 98.1 1.0 CD B:PRO311 4.7 61.1 1.0 C B:TYR309 4.7 57.7 1.0 C B:GLY306 4.8 68.9 1.0 N B:GLY312 4.9 70.5 1.0 N B:TYR309 4.9 46.9 1.0

Samarium binding site 6 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 6 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ B:Sm766 b:45.1 occ:1.00 OE2 B:GLU578 2.5 85.5 1.0 OE2 B:GLU575 2.9 91.3 1.0 OE1 B:GLU575 3.1 97.9 1.0 CD B:GLU578 3.2 92.3 1.0 OE1 B:GLU578 3.2 73.3 1.0 CD B:GLU575 3.4 98.7 1.0 CG B:GLU578 4.6 98.7 1.0 CG B:GLU575 4.9 98.7 1.0

Samarium binding site 7 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 7 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ C:Sm764 b:2.0 occ:1.00 OD1 C:ASP757 2.2 4.3 1.0 CG C:ASP757 2.3 6.4 1.0 OD2 C:ASP757 2.6 2.0 1.0 OD2 C:ASP648 2.6 32.5 1.0 OD1 C:ASP648 2.6 34.9 1.0 CG C:ASP648 2.9 51.2 1.0 CB C:ASP757 3.1 48.2 1.0 O C:ASP757 3.7 98.7 1.0 NE2 C:GLN743 4.2 45.1 1.0 CA C:ASP757 4.3 84.6 1.0 CB C:ASP648 4.4 53.3 1.0 C C:ASP757 4.4 94.2 1.0 N C:ASP757 4.9 94.7 1.0 CB C:SER644 5.0 63.9 1.0

Samarium binding site 8 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 8 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ C:Sm765 b:2.0 occ:1.00 OG1 C:THR310 1.8 2.0 1.0 OE1 C:GLU465 1.8 2.0 1.0 O C:THR310 1.9 2.0 1.0 OE2 C:GLU468 2.0 2.0 1.0 CD C:GLU465 2.5 14.7 1.0 OE1 C:GLU468 2.5 2.0 1.0 OE2 C:GLU465 2.5 2.0 1.0 CD C:GLU468 2.6 2.2 1.0 C C:THR310 2.6 42.6 1.0 CB C:THR310 2.7 25.1 1.0 O C:ASP307 3.0 59.1 1.0 CG2 C:THR310 3.0 70.7 1.0 CA C:THR310 3.1 45.7 1.0 N C:THR310 3.5 56.9 1.0 N C:PRO311 3.7 63.4 1.0 CG C:GLU465 3.8 46.9 1.0 CB C:ASP307 3.9 63.9 1.0 C C:ASP307 3.9 32.1 1.0 O C:PHE313 4.0 68.9 1.0 N C:ASP307 4.1 41.3 1.0 CG C:GLU468 4.1 48.4 1.0 CA C:ASP307 4.2 41.2 1.0 CA C:PRO311 4.3 48.0 1.0 OD1 C:ASP307 4.5 85.3 1.0 CG C:ASP307 4.6 79.6 1.0 C C:GLY306 4.7 47.1 1.0 CD C:PRO311 4.8 30.3 1.0 C C:TYR309 4.8 45.5 1.0 N C:TYR309 5.0 27.8 1.0 N C:GLY312 5.0 51.2 1.0 CB C:GLU465 5.0 17.2 1.0

Samarium binding site 9 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 9 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ C:Sm766 b:5.1 occ:1.00 OE2 C:GLU578 2.5 73.3 1.0 OE2 C:GLU575 3.0 79.7 1.0 OE1 C:GLU575 3.1 83.5 1.0 OE1 C:GLU578 3.1 89.7 1.0 CD C:GLU578 3.2 93.6 1.0 CD C:GLU575 3.4 88.5 1.0 CG C:GLU578 4.6 98.7 1.0 CG C:GLU575 5.0 88.4 1.0

Samarium binding site 10 out of 24 in the Crystal Structure of the Ectodomain of Human Transferrin Receptor


Mono view


Stereo pair view

A full contact list of Samarium with other atoms in the Sm binding site number 10 of Crystal Structure of the Ectodomain of Human Transferrin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ D:Sm764 b:2.0 occ:1.00 CG D:ASP757 2.4 9.8 1.0 OD1 D:ASP757 2.4 28.3 1.0 OD1 D:ASP648 2.5 2.0 1.0 OD2 D:ASP648 2.6 48.2 1.0 OD2 D:ASP757 2.7 2.0 1.0 CG D:ASP648 2.8 53.5 1.0 CB D:ASP757 3.1 45.1 1.0 O D:ASP757 3.8 86.8 1.0 NE2 D:GLN743 4.1 43.6 1.0 CB D:ASP648 4.2 53.4 1.0 CA D:ASP757 4.3 85.5 1.0 C D:ASP757 4.5 93.6 1.0 CB D:SER644 4.8 55.1 1.0 O D:SER644 4.9 42.0 1.0 N D:ASP757 5.0 95.3 1.0

C.M.Lawrence, S.Ray, M.Babyonyshev, R.Galluser, D.W.Borhani, S.C.Harrison. Crystal Structure of the Ectodomain of Human Transferrin Receptor. Science V. 286 779 1999.
ISSN: ISSN 0036-8075
PubMed: 10531064
DOI: 10.1126/SCIENCE.286.5440.779